The injury-ravaged San Francisco 49ers will again be missing multiple starters with injuries for the Thursday night game against the Los Angeles Rams.

Quarterback Brock Purdy will miss his third game of the season because of an injury to his toe. The Niners (3-1) also ruled out starting receivers Ricky Pearsall and Jauan Jennings for the division showdown, with Pearsall out because of a knee injury and Jennings with injuries to his ankle and ribs.

(L-R) Brock Purdy, Ricky Pearsall, Jauan Jennings Thearon W. Henderson/Sean Gardner/Logan Bowles/Getty Images

Purdy missed games in Week 2 and 3 with the injured toe before returning this past Sunday against Jacksonville. He came out of that game with more soreness and will be unable to play on a short week.

Mac Jones will start in Purdy's

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