The San Francisco 49ers (3-1) are visiting the LA Rams (3-1) Thursday night in a marquee matchup between division rivals. Kickoff from SoFi Stadium in Inglewood, California, is set for 8:15 p.m. ET (Prime Video). Let's analyze BetMGM Sportsbook's NFL odds around the 49ers vs. Rams odds and make our expert NFL picks and predictions for the best bets.

The 49ers suffered their first loss of the season Sunday, a home game against the Jacksonville Jaguars. Despite getting QB Brock Purdy back from a toe injury, the 49ers fell to Jacksonville, 26-21. That dropped the 49ers to 3-1, putting the first blemish on their record. RB Christian McCaffrey was the leading rusher and receiver with 49 yards on the ground and 92 yards receiving on 6 catches with 1 touchdown.

The Rams bounce

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