The Week 5 NFL schedule for the 2025 season brings some exciting matchups.

Browns rookie QB Dillon Gabriel is making his NFL debut in London against the Vikings. Old teammates in Carolina , QBs Baker Mayfield and Sam Darnold , will face off again in the Bucs-Seahawks matchup. And Commanders QB Jayden Daniels makes his return from injury against the Chargers.

We have you covered with everything you need to know. Our NFL Nation reporters take you inside the locker room with the best thing they heard this week, and ESPN Research provides a key stat to know and a betting nugget for each contest. Plus, analytics writer Seth Walder makes a bold prediction for each matchup, and fantasy analyst Eric Moody shares fantasy football intel. We also have Football Power Index (FPI

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