The San Francisco 49ers have been dealt several injuries this season, and the hits keep on coming as they head into Week 6 against the Tampa Bay Buccaneers. Two key players on offense have been ruled out , according to NFL Network's Ian Rapoport.

“QB Brock Purdy (toe) has been ruled out again, as has WR Ricky Pearsall . Mac Jones (oblique, knee) is the likely starting option, though he's listed as questionable,” Rapoport wrote on X, formerly Twitter.

Purdy missed last week against the Los Angeles Rams because of his toe injury after coming back the week prior. Purdy felt soreness in his toe after the game, and now it looks like the 49ers are trying to be more cautious than they were before, and they can with Mac Jones playing well this season. Article Continues Below

As for Pe

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