On Saturday, the Indiana Hoosiers (5-0, 2-0 in Big Ten) and Oregon Ducks (5-0, 2-0 in Big Ten), two of the best teams in college football, will fight for a chance to all but lock in both a Big Ten Championship Game appearance and a College Football Playoff berth.

The stakes could hardly be higher, especially for a matchup this early in the regular season.

The Hoosiers enter Autzen Stadium as a 7.5-point road dog against Oregon, while the over/under (55.5 points) indicates a high-scoring matchup.

Keep reading below for our Indiana vs. Oregon predictions, picks, and best bets breakdown for this blockbuster Big Ten bout in Week 7.

Indiana vs. Oregon Predictions and best bets

Indiana Hoosiers +7.5: -115 at BetMGM

Under 55.5 points: -115 at FanDuel

*Note: Odds are based on the best

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