Detroit Lions defensive end Aidan Hutchinson (97) looks to tackle Kansas City Chiefs quarterback Patrick Mahomes (15) during the second half at Arrowhead Stadium in Kansas City, Mo., Thursday, Sept. 7, 2023.

The Detroit Lions (4-1) visit the Kansas City Chiefs (2-3) in a Week 6 matchup on Sunday Night Football. Kickoff from GEHA Field at Arrowhead Stadium in Kansas City, Missouri., is for 8:20 p.m. ET (NBC). Let's analyze BetMGM Sportsbook's NFL odds around the Lions vs. Chiefs odds and make our expert NFL picks and predictions for the best bets.

The Lions put up 30 points for the fourth straight week in a 37-24 victory over the Cincinnati Bengals last week. QB Jared Goff was 19-for-23 for 258 yards, 3 TDs and no INTs. RB Jahmyr Gibbs had a lighter day with 12 carries for 54 yards, but he had 2 catches for 33 yards and a score. The Lions are littered with injuries as they have 11 guys on IR. They're down a starting corner, and both safeties are questionable - as well as their left tackle.

The Chiefs lost 31-28 on a late, crazy play by Jacksonville Jaguars QB Trevor Lawrence. He stepped on a lineman's foot and fell down, got up and ran into the end zone for the eventual winning score. QB Patrick Mahomes was 29-for-41 for 318 yards, 1 TD and 1 INT, and he rushed 6 times for 60 yards and another score. RBs Kareem Hunt and Isiah Pacheco combined to rush 14 times for 85 yards and 2 TDs. TE Travis Kelce added 7 grabs for 61 yards and a score. They have one more week without top wideout Rashee Rice.

The Chiefs lead the all-time series 9-6, but the Lions won 21-20 in Kansas City in 2023.

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Lions at Chiefs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:06 a.m. ET.

  • Moneyline (ML): Lions +120 (bet $100 to win $120) | Chiefs -145 (bet $145 to win $100)
  • Against the spread (ATS): Lions +2.5 (-110) | Chiefs -2.5 (-110)
  • Over/Under (O/U): 53 (O: -110 | U: -110)

Lions at Chiefs key injuries

Lions

  • CB Terrion Arnold (shoulder) out
  • S Brian Branch (ankle) questionable
  • OT Taylor Decker (shoulder) questionable
  • S Kerby Joseph (knee) questionable
  • CB Avonte Maddox (hamstring) questionable
  • WR Kalif Raymond (neck) questionable

Chiefs

  • WR Rashee Rice (suspension) out

Lions at Chiefs picks and predictions

Prediction

Lions 38, Chiefs 31

Moneyline

The Lions' offense hasn't been stopped, and the Chiefs defense hasn't been able to get stops. The Lions' secondary is also a problem, so this one shapes up to be a shootout. In a shootout, I'm taking the team that can get stops - and Kansas City hasn't proven it can do it.

Give me the LIONS (+120).

  • LIONS AT CHIEFS: Best prop bests

Against the spread

I'll take PATRICK MAHOMES OVER 28.5 RUSHING YARDS (-110). He had 45 rushing yards against the Lions last time they played in 2023. His line has been a constant problem with penalties and shoddy play. Mahomes has only been sacked 7 times, but he has ran for his life a lot and led the team in rushing most weeks.

Over/Under

We touched on this, but KC's defense can't stop anyone, and Detroit has posted 30 in 4 straight games.

Give me the OVER 53 (-110).

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This article originally appeared on Sportsbook Wire: Detroit Lions at Kansas City Chiefs odds, picks and predictions

Reporting by Ryan Dodson, Sportsbook Wire / Sportsbook Wire

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