With so much discourse surrounding the realism and emotional gravitas of 2025's HBO Max drama The Pitt, it inevitably draws out competitors further into the year. While medical dramas taking place at emergency rooms inevitably pull on the heartstrings due to the emotional turmoil of the work involved, any series can ultimately still break the hearts of its viewers.

While it's easy to practically recite the saddest moments of The Pitt , there's something truly striking about when a predominantly lighthearted series winds up a gut-punch. It's especially true when it's an animated series as charming and wonderful as Spy x Family . But the real fans knew, this episode of Spy x Family packed some of 2025's greatest emotional damage.

The Pitt Has a New Rival for 2025's Saddest

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