KANSAS CITY, Mo. — This month, 25-year-old Madison Mcmanness found herself in a place she never wanted to see again: drug rehab.

"I didn't think that I would be there again," Mcmanness said. "It was really hard lying in the detox for three days, just catatonic. Everything was on fire. It hurt. I just didn't want to do it anymore."

She was six and a half years clean from heroin when a friend suggested she try 7-OH to help with anxiety.

"As soon as I took that 7-OH, it was like taking heroin again for the first time," she said.

7-OH, short for 7-hydroxymitragynine, comes from kratom, a tropical tree. It's a psychoactive compound that has similar effects in the brain as opioids. Kratom and its derivatives like 7-OH are unregulated by the FDA, but the agency has repeatedly said it's workin

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