It's not a primetime game, but the contest many will highlight with their Week 9 NFL picks is Chiefs vs. Bills at 4:25 p.m. ET on Sunday. It's become, arguably, the league's preeminent rivalry, and the latest installment has Kansas City as 1.5-point road favorites, per the Week 9 NFL odds. Meanwhile, other contests to be of high interest with NFL bets involve a pair of West Coast teams flying east in 49ers vs. Giants (+2.5) and Seahawks vs. Commanders (+3.5).

If looking for a divisional rivalry when scanning the latest Week 9 NFL lines, you'll just find one in Lions vs. Vikings. Any rest advantage Minnesota hoped for from playing last Thursday is negated by Detroit coming off a bye, and the Lions are one of the biggest favorites, per the Week 9 NFL spreads, as they're giving 8.5 points. O

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