The 2025-26 college basketball season gets underway on Monday, Nov. 3, and the defending champion and third-ranked Florida Gators will begin their title defense against the No. 13 Arizona Wildcats in a 2025 Hall of Fame Series matchup at 7 p.m. ET at T-Mobile Arena in Las Vegas. That's the headliner of the day, and the Gators are the 3.5-point favorites in that one in the latest college basketball odds for Monday, with the over/under at 163.5.

Other college basketball lines of note include No. 8 BYU (-9.5) vs. Villanova and No. 7 Michigan (-24.5) vs. Oakland. With action unfolding throughout the day, and plenty of early-season mismatches on the board, what are the college basketball best bets for Monday? Before locking in any college basketball picks, you'll want to see the college baske

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