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The Carolina Panthers will visit the San Francisco 49ers for a Monday Night Football game.

This Week 12 matchup is scheduled for Monday, Nov. 24, 2025, at 8:15 p.m.

The game will be broadcast on ESPN and can be streamed on ESPN+ and NFL+.

Entering the game, the San Francisco 49ers have a 7-4 record, while the Carolina Panthers are 6-5.

Monday Night Football and the 2025 NFL season continue tonight when the Carolina Panthers visit the San Francisco 49ers at Levi's Stadium for a Monday Night Football battle on ESPN .

Here's what you need to know about tonight's matchup , how to watch the 49ers vs. the Panthers , the NFL Week 12 schedule , how to watch Monday Night Football , the Week 13 TV lineup and more.

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