Monday Night Football arrives with a heavyweight matchup between the Carolina Panthers and San Francisco 49ers, and Bet365 has a featured first touchdown scorer price on Christian McCaffrey at +220.

Bet365 first touchdown spotlight: Christian McCaffrey (+220)

In the Bet365 market shown in the screenshot, Christian McCaffrey is priced at +220 to score the first TD of the game—consistent with Dimers’ simulation, which gives him a 19.5% probability , the highest among all players.

Game details:

Teams: Carolina Panthers vs. San Francisco 49ers

Date: Monday, November 24, 2025

Kickoff: 8:15 p.m. EST

Location: Levi’s Stadium

NFL standings: Current NFL division standings

NFL injuries: Latest official NFL injury report

Odds

Spread: Panthers +7.5 (-112), 49ers -7.5 (-104)

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