Nov 22, 2025; Tucson, Arizona, USA; Arizona Wildcats quarterback Noah Fifita (1) against the Baylor Bears in the second half at Casino Del Sol Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images

It's time for the Territorial Cup, and this time, it's a ranked matchup.

Arizona State (8-3, 6-2 Big 12) has been banged up this season and is currently without quarterback Sam Leavitt, but it continues to find ways to win games. Now, the defending Big 12 champions play host to archrival Arizona (8-3, 5-3 Big 12) to conclude the regular season.

If you are looking for some betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Arizona State vs. Arizona game odds:

All college football odds via BetMGM

  • Spread: Arizona -1.5 (-115), Arizona State +1.5 (-105)
  • Money Line: Arizona -120, Arizona State +100
  • Over-Under: Over 48.5 (-110), Under 48.5 (-110)

Arizona State vs. Arizona prediction, pick:

On paper, this seems like a good matchup for the Wildcats. Their defense has been fantastic, especially down the stretch this season, and that's not particularly encouraging with it being the Jeff Sims show at Arizona State. While the Wildcats' offense hasn't been as good, Noah Fifita is having a solid bounce-back season.

Arizona State is still no slouch, though. It boasts a respectable defense and a tough running game. The Sun Devils have found ways to win this season, even with quite a few injuries, and I think they'll find a way to get the job done here in a rivalry showdown.

Prediction: Arizona State 23, Arizona 21

Best Bet: Arizona State +1.5, Under 48.5

Arizona State vs. Arizona channel, start time, streaming:

Time: 9 p.m. ET

TV Channel: FOX

Live Stream: Fox Sports App

Watch Arizona State vs. Arizona on FuboTV (Free Trial)

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: Arizona State vs. Arizona: College Football Betting Odds, Pick

Reporting by Tyler Nettuno, College Sports Wire / College Sports Wire

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