The top Week 13 defense streamers - fantasy football D/ST pickups, streamers and starts for 2025. Target these fantasy DST streaming options with strong matchups.

Fantasy managers looking to clinch a spot in the fantasy playoffs will have to target the right defense to give their lineup a boost.

In this piece, we identify four of the top streaming options available in fewer than 65% of Yahoo leagues.

Who should fantasy managers look to target on the waiver wire and plug into their starting lineup? Let's dive in! Be sure to check all of our fantasy football rankings for 2025:

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