The M4 is closed eastbound between J18 (Bath and J17 (Chippenham) after reports of a serious incident in the early hours of Sunday morning.
A single vehicle reportedly left the road near Leigh Delamere services at about 2am. Emergency services are investigating.
It is likely the road will be closed well into Sunday.
"At around 02:00 Wiltshire Police responded to a serious single vehicle collision involving a car which has left the eastbound carriageway near Leigh Delamere services," a statement on the National Highways website said.
"The carriageway has been closed to allow Wiltshire Police, Dorset and Wiltshire Fire and Rescue Service and South West Ambulance Service to work at the scene of the collision. National Highways Traffic Officers are also on scene and are assisting the emerg

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