By FRED SHUSTER

One of two physicians charged in “Friends” star Matthew Perry’s death from a ketamine overdose is expected to be sentenced Wednesday in downtown Los Angeles on federal charges of illegal distribution of the surgical anesthetic.

Salvador Plasencia, 43, of Santa Monica, pleaded guilty in July to four federal counts of distribution of ketamine, which is used as a therapy for depression, but also as a so-called party drug.

The disgraced doctor faces up to 40 years in prison, although he is not expected to receive such a lengthy sentence, and a fine of at least $2 million, according to his plea agreement.

Five defendants were charged in Perry’s death and subsequently pleaded guilty. The lead defendant, Jasveen Sangha — dubbed the “Ketamine Queen” — will face up to 65 years i

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