Unbeaten squads meet in an early tip on Saturday as the top-ranked Purdue Boilermakers host the No. 10 Iowa State Cyclones. Iowa State is off to a strong start with wins over Mississippi State, Creighton, St. John's and Syracuse already on its resume. Purdue, meanwhile, has knocked off Alabama, Rutgers, Memphis and Texas Tech thus far. Both teams have covered in their last three games as well, setting up a heavyweight, top-10 battle.

Tipoff from Mackey Arena is set for noon ET. The Boilermakers are 5.5-point favorites in the latest Purdue vs. Iowa State odds, while the over/under is 154.5. Before making any Iowa State vs. Purdue picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model .

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