Los Angeles County deputies are in pursuit of a driver near Granada Hills.
It's unclear where the chase began.
With SkyCal overhead, the driver, behind the wheel of a large pickup truck, could be seen driving on the wrong side of the road.
At one point, a person who appeared to be a passenger briefly exited the truck and tried to open the door of a white sedan. When the door did not open, they got back into the truck, which took off again heading against traffic on the 405 Freeway in Sylmar.
They again attempted to get into another vehicle, a white semi truck, just moments after the first attempt.
After the second unsuccessful attempt, they crashed head-on into a different big rig which had an open passenger window. Both the driver and passenger were able to get into the truck, which