TOPLINE:
Among normotensive patients with severe obstructive sleep apnea (OSA) and a dipping blood pressure (BP) pattern, continuous positive airway pressure (CPAP) prevented increases in BP over a 3-month follow-up period, with significant reductions in nighttime diastolic BP compared with usual care.
METHODOLOGY:
Researchers conducted a randomized, prospective, controlled trial to assess the effect of CPAP on BP in normotensive individuals with severe OSA and a dipping BP pattern.
Overall, 60 normotensive adult patients (mean age, 52.2 years; 66.7% men) with severe OSA (apnea-hypopnea index, ≥ 30 per hour) and a dipping BP pattern (reduction of ≥ 10% from daytime to nighttime BP) were randomly assigned to receive either CPAP or usual care for 12 weeks.
Primary outcomes were changes