TOPLINE:

In patients hospitalized with acute kidney injury (AKI) and liver cirrhosis, higher levels of peak serum cystatin C were associated with an increased risk for inhospital mortality, whereas lower baseline levels of the biomarker predicted better odds of renal recovery.

METHODOLOGY:

Cystatin C, a 13-kDa nonglycosylated protein produced by all nucleated cells, has been reported as an early predictor of AKI development in patients with liver cirrhosis; however, little is known about its role in predicting AKI recovery in this population.

Researchers conducted a retrospective cohort study to investigate whether serum levels of cystatin C could predict kidney function recovery and mortality in adults with liver cirrhosis and AKI (N = 209; 97 women; mean age, 56 years) hospitalized b

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