Key takeaways:

Cardiovascular disease is a leading cause of mortality in systemic lupus erythematosus.

Controlling SLE disease activity can prevent cardiovascular events.

Controlling disease activity in systemic lupus erythematosus is one of many ways to prevent cardiovascular events in these patients, according to a presenter at the 2025 AWIR annual conference.

“Organ damage occurs early and is associated with significant morbidity and mortality in SLE,” Maria Dall'Era, MD, chief of the University of California, San Francisco Division of Rheumatology and director of the UCSF Lupus Clinic, told Healio. “Cardiovascular disease and damage is a leading cause of mortality in SLE.”

It has long been understood that cardiovascular risk is elevated in lupus, according to Dall’Era.

“Young

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