Multiple fatalities , including children, have been reported in the serious crash of a tour bus in Upstate New York on Friday afternoon, Aug. 22, police say.

A chartered tour bus crashed on Interstate 90 in Pembroke, New York, the New York State Police said in a news release . Returning to New York City from Niagara Falls, the bus lost control, entered the median, and crossed the southern shoulder before overturning, multiple witnesses reported to state police.

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