STAND-UP comedian Reggie Carroll has been shot dead in Mississippi with a male suspect charged with murder.

Carroll, 52, was gunned down in Southhaven as his family and heartbroken friends pay tribute to the self-proclaimed "Knockout King of Comedy ".

The popular Baltimore-born comedian was pronounced dead on Wednesday, the Southhaven Police Department confirmed.

Officers responded to Burton Lane after reports of a shooting as they found "one male victim suffering from gunshot wounds," cops said.

Carroll was alive when cops first discovered him but passed away a short time later from his injuries.

Fellow comedian and Oscar winner Mo’Nique paid tribute to Carroll after his tragic passing.

She hailed him as a "brother in comedy," in a touching Instagram post.

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