Nearly 1 in 3 Americans has high cholesterol, elevating their risk of heart attack and stroke. While statins remain the gold standard for managing cholesterol, many people turn to natural remedies like berberine, a plant-based compound used for centuries in Ayurveda and traditional Chinese medicine.

1. It Activates AMPK

Berberine activates AMPK ( adenosine monophosphate-activated protein kinase ), a key enzyme that helps regulate metabolism . AMPK acts like a master switch for energy balance, helping your body better optimize metabolic regulation, potentially lowering cholesterol and triglyceride levels .

AMPK Is Berberine's Star Player

AMPK helps your cells burn fat for energy instead of storing it. Activating this enzyme may explain why berberine has the power to lower chol

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