The San Francisco 49ers came into Week 1 with a few injuries on offense, and things did not get better during their game against the Seattle Seahawks as George Kittle went down , according to ESPN's Adam Schefter.

“George Kittle is out for the rest of today’s game due to a hamstring injury,” Schefter wrote on X, formerly Twitter.

The fact that Kittle was ruled out shows that it may be something bigger than just a minor hamstring injury. Hamstrings are always tough to diagnose, as it could take up to days or even weeks for players to get back to full speed. There should be more on Kittle's injury after the game. Article Continues Below

There was already uncertainty coming into the game on whether Christian McCaffrey was going to play after being added to the injury report late i

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