Key points

Exercise protects cells and slows epigenetic aging.

Vigorous activity triggers youth-preserving hormesis.

Staying fit rejuvenates the epigenome and supports longevity.

Aging is inevitable, but how fast your cells age isn't set in stone. On a molecular level, biological age is measured using something called the epigenetic clock, which isn't tied to chronological age in calendar years. This clock measures chemical changes, such as DNA methylation patterns , and gauges a person's "youthfulness" or "agedness" based on their epigenome, the system that controls how our genes are expressed, irrespective of birth-certificate age.

As chronological time marches on, how can you slow your epigenetic clock? Research suggests that lifestyle choices (e.g., diet , exercise, stress

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