San Francisco 49ers quarterback Brock Purdy was among several key players ruled out for the team's Thursday Night Football game against the NFC West Division rival Los Angeles Rams, NFL Network 's Ian Rapoport reports.

Wide receivers Jauan Jennings (ankle, ribs), Ricky Pearsall (knee) and Jordan Watkins (calf), as well as defensive end Robert Beal (ankle), will also be inactive on Thursday (October 2) night, according to Rapoport.

"The #49ers have ruled QB Brock Purdy out vs. the #Rams ," Rapoport wrote on his X account Wednesday (October 1). "In addition, the #49ers have ruled out Jauan Jennings (ankle, ribs) WR Ricky Pearsall (knee), WR Jordan Watkins (calf), and DE Robert Beal (ankle)."

Purdy initially suffered shoulder and toe injuries during the Niners' Wee

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