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A short week was not kind to the San Francisco 49ers , as the team will be without key offensive pieces, including quarterback Brock Purdy, against the Los Angeles Rams on "Thursday Night Football."

Wide receivers Ricky Pearsall and Jauan Jennings will also be unavailable for the 49ers on Thursday night.

Purdy missed Weeks 2 and 3 after suffering a toe injury in the season opener but returned in Week 4 against the Jacksonville Jaguars . During the 26-21 loss, Purdy’s toe injury flared up again.

In turn, Mac Jones will make his third start of the season.

He filled in for Purdy in the previous games, completing 66% of his passes for 563 yards with four touchdowns and one interception over that span. The 49ers won both

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