A woman has been charged with the murder of a man believed to be her partner after an incident in South Australia's mid-north on Friday.

Police said the man, 52, was reported unconscious at a house in Dorothy Street, Port Pirie South, around 2:15pm on Friday.

"Despite the efforts of paramedics, the 52-year-old man could not be revived and was pronounced deceased at the scene," police said in a statement.

Police then arrested a 42-year-old woman and charged her with murder.

Police said they believe the man and woman lived together at the address and were in a domestic relationship.

"Detectives from Major Crime Investigation Branch and officers from Forensic Response Section have travelled to the scene to assist with the ongoing investigation into the circumstances surrounding the man's

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