The Syracuse Orange (3-7) and No. 9 Notre Dame Fighting Irish (8-2) meet Saturday at Notre Dame Stadium in Notre Dame, Indiana. Kickoff is set for 3:30 p.m. ET (NBC / Peacock). Let's analyze BetMGM Sportsbook's NCAA football odds around the Syracuse vs. Notre Dame odds and make our expert college football picks and predictions for the best bets.

Syraucse was blown out by the No. 15 Miami Hurricanes 38-10 on Nov. 11, but covered as a 28.5-point road underdog as the Over (46.5) cashed. The Orange had a Week 12 bye. They come into this game having lost 6 straight and going 2-4 against the spread (ATS) in those. Syracuse's main issue has been on the defensive end, allowing at least 30 points in 6 of its 10 games this season.

The Fighting Irish have rebounded well after starting

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