One of the hottest topics in Hollywood: The type 2 diabetes drug Ozempic and its fellow semaglutide drugs, such as Wegovy, as well as similar GLP-2 drugs containing tirzepatide, such as Mounjaro and Zepbound. The use of either prescription — which Dr. Ania Jastreboff tells PEOPLE are "nutrient-stimulated, hormone-based medications" that target the brain and affect satiety. As a result, the GLP-1 drugs have become popular in Hollywood for weight loss both for those who only need to lose a few pounds as well as for those who have been open about their long-term weight struggles.

"The Hollywood trend is concerning," Dr. Caroline Apovian, co-director of the Center for Weight Management and Wellness at the Brigham and Women's Hospital in Boston, tells PEOPLE of the target audience for the

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