By Sandee LaMotte, CNN

(CNN) — At 62, Phyllis Jones felt trapped in darkness. She was traumatized by her mother’s recent death, ongoing pandemic stress and an increasingly toxic work environment . A sudden panic attack led to a medical leave.

Her depression worsened until the day her 33-year-old son sadly told her, “Mom, I didn’t think I would have to be your caregiver at this stage in your life.”

“For me, that was the wake-up call,” Jones, now 66, told CNN. “That’s when I found the POINTER study and my life changed. What I accomplished during the study was phenomenal — I’m a new person.”

The Protect Brain Health Through Lifestyle Intervention to Reduce Risk, or US POINTER study , is the largest randomized clinical trial in the United States designed to examine whether lifestyle i

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