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Researchers identified how the medication hydralazine works at the molecular level in the body.
Hydralazine is commonly used to treat high blood pressure and preeclampsia.
Understanding its mechanism revealed the potential it has for stopping glioblastoma — an aggressive brain tumor — growth.
The blood pressure drug hydralazine has been around for more than 70 years, but scientists did not previously know how it worked.
This is not uncommon, and the researchers have pointed out that between 10 and 20% of drugs have an unknown mechanism of action.
Researchers at the University of Pennsylvania recently uncovered hydralazine’s mechanism and also discovered that the drug has the potential to stop the growth of glioblastoma , an aggressive brain tumor.
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