Key Takeaways

Nicotine has a half-life of about two hours and can stay in the blood for about one to three days. Cotinine, a byproduct of nicotine, has a half-life of 18 hours and can last for several days.

Withdrawal symptoms of nicotine can start within hours and peak within the first few days, but diminish over time.

Nicotine replacement therapy, counseling, and other strategies may help with quitting smoking and with nicotine withdrawal symptoms.

Nicotine remains in the bloodstream for about one to three days, though most of it is usually cleared within one day. However, cotinine (nicotine's metabolite) can last in the body for several days.

How Long Nicotine Lasts In Your Body

Nicotine has a half-life of about two hours (meaning half of it is gone from your body about two hours

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